
Overview
5-Amino-1MQ (5-Amino-1-methylquinolinium) is a synthetic small molecule that functions as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme implicated in metabolic regulation and energy homeostasis. By inhibiting NNMT, 5-Amino-1MQ helps conserve nicotinamide and maintain NAD⁺ levels, supporting mitochondrial bioenergetics and metabolic homeostasis in preclinical models. This compound is provided exclusively for laboratory research purposes and is not intended for human consumption, medical, or diagnostic applications.
Research Focus
In preclinical and laboratory studies, 5-Amino-1MQ has been investigated in relation to:
-
Metabolic regulation – exploring its role in glucose metabolism, fatty acid oxidation, and insulin sensitivity.
-
Adipose tissue dynamics – examining its effects on fat cell size and adipocyte function.
-
Mitochondrial function – studying its impact on mitochondrial efficiency and energy production.
-
Aging research – analyzing its potential to support longevity-associated pathways by preserving NAD⁺ levels.
Key Features
-
Selective NNMT inhibitor
-
Synthetic small molecule with high purity
-
Supplied in lyophilized powder form for laboratory stability
-
Manufactured to stringent quality standards
Specifications
-
Synonyms: 5-Amino-1-methylquinolinium
-
Molecular Formula: C₉H₁₀N₂
-
Molecular Weight: ~174.2 Da
-
Purity: ≥98% (HPLC)
-
Form: Lyophilized powder
-
Storage: Store at –20°C; stable under recommended conditions
-
Intended Use: Research use only. Not for human consumption, medical, or veterinary use.
Disclaimer
This material is supplied for laboratory research purposes only. It is not a drug, food, or cosmetic. The buyer assumes all responsibility for safe handling and lawful use.