Overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded by the mitochondrial genome. It plays a central role in metabolic homeostasis, helping cells adapt to energy stress and improve efficiency. MOTS-c is primarily studied in laboratory settings for its potential applications in aging, insulin resistance, cardiovascular disease, and inflammation. This product is intended strictly for scientific research and is not for human consumption, medical use, or diagnostic purposes.

Research Focus
In preclinical and laboratory studies, MOTS-c has been investigated in relation to:

• Metabolic regulation – exploring its role in glucose metabolism, fatty acid oxidation, and insulin sensitivity.

• Aging research – analyzing its potential effects on age-related diseases, including diabetes, cardiovascular diseases, osteoporosis, and postmenopausal obesity.

• Inflammatory response – studying its impact on pro-inflammatory cytokines and anti-inflammatory cytokines.

• Exercise physiology – examining its expression in response to stress or exercise and its translocation to the nucleus, where it regulates the expression of stress adaptation-related genes with antioxidant response elements (ARE).

Key Features

• Mitochondrial-derived peptide

• Research-grade peptide supplied in lyophilized form

• Manufactured to high-purity standards

Specifications

• Synonyms: Humanin-like 13 (HN13)

• Molecular Formula: C₈₈H₁₃₆N₂₄O₂₆

• Molecular Weight: ~1,800 Da

• Sequence: 16 amino acids encoded by mitochondrial 12S rRNA gene

• Purity: ≥98% (HPLC)

• Form: Lyophilized powder

• Storage: Store at –20°C; stable under recommended conditions

• Intended Use: Research use only. Not for human consumption, medical, or veterinary use.

Disclaimer
This material is supplied for laboratory research purposes only. It is not a drug, food, or cosmetic. The buyer assumes all responsibility for safe handling and lawful use.